Best Hotels in Florence, South Carolina

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Nestled in the lively heart of the Pee Dee region, Florence is a hidden gem of the Southeast, offering a unique blend of historical charm, modern convenience, and Southern hospitality. This vibrant city acts as a crossroads of culture and commerce, making it an ideal destination for both leisure and business travelers. Finding the perfect place to stay is crucial to experiencing all that Florence has to offer, and fortunately, the city boasts an array of hotels catering to a variety of tastes and budgets.

From luxurious accommodations with all the amenities to cozy, budget-friendly hotels, Florence ensures every visitor finds a comfortable home away from home. Many of these hotels are conveniently located near the city’s most popular attractions, including the Florence Museum, the War Between the States Museum, and the Florence Civic Center, making it easy for guests to explore. Recommendations for the best places to stay can help travelers make the most of their visit, whether they're here for the rich history, the bustling economy, or the warm climate.

Insights into the local hotel scene reveal a commitment to quality and service, with many establishments offering special touches that highlight the charm of the South. From boutique hotels with local character to nationally recognized brands that guarantee a certain standard of comfort, Florence’s accommodations are designed to satisfy diverse traveler needs. This guide aims to provide an overview of the top hotels in Florence including insights and recommendations that will help you choose the perfect base for your adventures in this enchanting city.

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Our Top 7

(Sorted by rating & number of reviews)

1. Staybridge Suites - Florence Center, An Ihg Hotel
2. Red Roof Inn Florence Civic Center
3. Towneplace Suites By Marriott Florence
4. Home2Suites By Hilton Florence
5. Hampton Inn & Suites Florence-North-I-95
6. Hotel Florence, Tapestry Collection By Hilton
7. Sleep Inn Florence

Luxury Hotels in Florence, South Carolina

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Florence
Jan 16, 2026 - Jan 17, 2026

Staybridge Suites - Florence Center, An Ihg Hotel

9.2

Good

(1391 Reviews)

+ 76 photos
Staybridge Suites Florence - Center offers families the perfect blend of home-like comfort and hotel luxury. Each suite is designed with space and convenience in mind, featuring fully equipped kitchens, separate living areas, and comfortable sleeping arrangements for the whole family. The hotel's complimentary breakfast buffet is a hit among guests of all ages, providing a great start to a day of exploration. Children will enjoy the outdoor pool and the on-site movie theater, while parents can take advantage of the fitness center and laundry facilities. Staybridge Suites is ideally located near family-friendly attractions, including the Florence Railroad Museum and Timrod Park. For families seeking a comfortable and convenient base in Florence delivers on all fronts.
Address: 150 Westpark Drive
Rating: Good 9.2 (1391 Reviews)
Rooms: 112
Price: From 159$

Red Roof Inn Florence Civic Center

6.4

Good

(864 Reviews)

+ 43 photos
For those seeking convenience and value, Red Roof Inn Florence - Civic Center delivers both. Situated close to the Florence Civic Center and within walking distance of various dining options, this hotel offers comfortable, pet-friendly accommodations without the hefty price tag. Rooms feature free Wi-Fi, flat-screen TVs, and cozy bedding, ensuring a good night's sleep. The hotel's commitment to providing clean, affordable lodging makes it a great choice for travelers looking to maximize their stay. Red Roof Inn Florence - Civic Center exemplifies how budget accommodations can still meet and exceed guest expectations.
Address: 2690 David Mcleod Blvd
Rating: Good 6.4 (864 Reviews)
Rooms: 112
Price: From 47$

Family-Friendly Hotels in Florence, South Carolina

Families traveling to Florence will find a welcoming array of accommodations designed to cater to guests of all ages. These family-friendly hotels offer spacious rooms, kid-focused amenities, and convenient locations close to attractions that will delight younger visitors. From pools and play areas to family suites with kitchenettes, the goal is to make every family's stay as comfortable and enjoyable as possible. Parents can also appreciate the added value of complimentary breakfast options and free Wi-Fi, ensuring a hassle-free experience. Explore the best family-friendly hotels in Florence and prepare for a memorable getaway that will please both adults and children alike.

Towneplace Suites By Marriott Florence

7.9

Good

(80 Reviews)

+ 29 photos
TownePlace Suites by Marriott Florence creates a home-away-from-home experience for both guests and their pets. Offering spacious, pet-friendly suites with fully equipped kitchens, this hotel makes it easy to maintain your routine while on the road. A pet fee applies, but the welcoming nature of the hotel and its staff, along with amenities like an outdoor pool and fitness center, make it worth it. The hotel’s proximity to local parks allows for enjoyable walks and a chance to explore Florence with your pet by your side. TownePlace Suites by Marriott Florence understands that pets are part of the family, ensuring a comfortable stay for all.
Address: 2650 Hospitality Boulevard
Rating: Good 7.9 (80 Reviews)
Rooms: 89
Price: From 172$

Home2Suites By Hilton Florence

8.2

Good

(388 Reviews)

+ 49 photos
Home2 Suites by Hilton Florence caters to families looking for flexibility and freedom during their stay in Florence extended-stay hotel features spacious suites with modular furniture, fully equipped kitchens, and ample room for families to spread out and relax. The innovative saline pool is perfect for kids to splash in, while parents can utilize the outdoor grilling areas for a fun family meal. The hotel's focus on sustainability and eco-friendly practices will appeal to environmentally conscious families. Its location is conveniently close to the Florence Center, offering easy access to entertainment and shopping options. Home2 Suites by Hilton Florence strikes the perfect balance between home-like comforts and the excitement of travel.
Address: 900 Woody Jones Boulevard
Rating: Good 8.2 (388 Reviews)
Rooms: 83
Price: From 139$

Budget-Friendly Hotels in Florence, South Carolina

For travelers keen on exploring Florence without breaking the bank, a variety of budget-friendly hotels offer comfortable accommodations at an affordable price. These hotels prove that economical does not mean compromising on cleanliness, comfort, or convenience. Guests can expect essential amenities like free Wi-Fi, complimentary breakfast, and efficient service, ensuring a pleasant stay. Located within easy reach of Florence's attractions and dining options, these budget-friendly hotels are perfect for road trippers, solo travelers, and anyone looking to extend their stay in Florence without a hefty price tag. Dive into our top picks for budget-friendly hotels that manage to offer value without skimping on the essentials.

Hampton Inn & Suites Florence-North-I-95

8.4

Good

(170 Reviews)

+ 94 photos
Hampton Inn & Suites Florence-North/I-95 makes traveling with family a breeze, thanks to its welcoming atmosphere and thoughtful amenities. Families will appreciate the comfortable rooms, equipped with cozy beds and modern amenities, ensuring a restful night for everyone. The complimentary hot breakfast offers a variety of choices to satisfy picky eaters, and the indoor pool provides year-round fun for kids. Strategically located near the I-95, the hotel gives easy access to local dining and attractions, such as the Lynches River County Park. Hampton Inn & Suites understands the needs of families, offering cribs and high chairs upon request, making it an excellent choice for a fuss-free stay in Florence .
Address: 1735 Stokes Road
Rating: Good 8.4 (170 Reviews)
Rooms: 136
Price: From 159$

Hotel Florence, Tapestry Collection By Hilton

8.1

Good

(154 Reviews)

+ 206 photos
Hotel Florence presents an exquisite blend of historic charm and modern luxury in the lively heart of Florence boutique hotel offers an intimate and refined atmosphere, with each of its rooms and suites displaying a unique layout and sophisticated décor. Guests can indulge in top-notch amenities, including premium bedding, spa-inspired bathrooms, and complimentary Wi-Fi, ensuring a comfortable and connected stay. The on-site restaurant, Victor's Bistro, serves locally sourced cuisine in an elegant setting, making it a favorite among guests and locals alike. Additionally, Hotel Florence's proximity to the city's main attractions and business district makes it a perfect choice for travelers seeking both relaxation and convenience. Experience Southern hospitality at its finest while enjoying the lavish comforts that make Hotel Florence a standout.
Address: 126 West Evans Street
Rating: Good 8.1 (154 Reviews)
Rooms: 62
Price: From 149$

Pet-Friendly Hotels in Florence, South Carolina

Traveling with pets can add an extra layer of joy to your trip, and in Florence numerous hotels welcome four-legged friends with open arms. Pet-friendly hotels in Florence provide various amenities to ensure both you and your pets have a comfortable stay, including designated pet areas, treats, and sometimes even pet services. Proximity to parks and outdoor spaces also means plenty of opportunities for walks and adventures. For pet owners, finding the right place to stay means considering the needs of their furry companions, and these hotels go out of their way to accommodate those needs. Explore our recommended pet-friendly hotels in Florence, where pets are not just allowed but celebrated.

Sleep Inn Florence

7.5

Good

(208 Reviews)

+ 73 photos
Sleep Inn Florence offers a cozy and inviting atmosphere for travelers looking for value in Florence hotel's modern rooms are designed with guest comfort in mind, featuring plush bedding, workspaces, and complimentary Wi-Fi. Guests can start their day with a free hot breakfast before exploring nearby attractions or heading to the Florence Regional Airport, just a short drive away. The outdoor swimming pool and fitness center provide leisure opportunities right on-site. Budget-conscious travelers will appreciate Sleep Inn Florence for its combination of essential amenities and affordability.
Address: 1833 Florence Park Dr. I-95 & Us 52
Rating: Good 7.5 (208 Reviews)
Rooms: 106
Price: From 80$